External Source:
Grand challenges integration | PLoS Medicine | Volume 10, Issue 4, pp. 1-6

“Achieving desired outcomes for priority programs will be difficult without managing mental, neurological, and substance use (MNS) disorders. At a minimum, packages of care for MNS disorders should be parceled with effective interventions in primary care or other priority health delivery platforms.”


Mental illnesses frequently co-occur with peripartum conditions, HIV-related disease, and noncommunicable diseases. Care for mental disorders should be integrated into primary care and other global health priority programs. Integration of care for mental, neurological, and substance use (MNS) disorders should 1) occur through intersectoral collaboration and health system-wide approaches, 2) use evidence-based interventions, 3) be implemented with sensitivity to environmental influences, and 4) attend to prevention and treatment across the life course. Integration of care for MNS disorders with care for other conditions can occur through assimilation of activities, policies, or organizational structures at local, national, and global levels. Plans for health-related development targets post-2015 should consider the tremendous burden of disability associated with MNS disorders and co-morbid conditions. This paper is the first in a series of five articles providing a global perspective on integrating mental health.

Grand Challenges in Global Mental Health

The Grand Challenges in Global Mental Health initiative has identified priorities for research in the next 10 years that will make an impact on the lives of people living with MNS disorders. The initiative’s scope is global, covers the full range of MNS disorders, and is intended to build a wide-ranging community of research funders across global mental health. The 2011 Nature article introducing the initiative is available, on behalf of the Scientific Advisory Board and Executive Committee of the Grand Challenges in Global Mental Health.

The initiative has been supported by:

  • US National Institute of Mental Health (NIMH)
  • Global Alliance for Chronic Disease (GACD)
  • Wellcome Trust
  • McLaughlin-Rotman Centre for Global Health
  • Fogarty International Center