External Source:
H3Africa Report

“H3Africa should be about solving the health problems of African people by understanding the complex interactions between genetic and nongenetic factors and not just about documenting human genome variation […] Moreover, several chronic conditions, including stroke, hypertension, CVD, and type 2 diabetes, present significant opportunities that could generate data beneficial to populations outside of Africa.”

Released in January 2011 by the National Institutes of Health (NIH) and the Wellcome Trust, this white paper discusses key findings and future opportunities for Human Heredity and Health in Africa (H3Africa), a genomics-focused, population-based research initiative across diseases, including NCDs.

The H3Africa initiative was formed to address under-representation of African populations in global disease research, and facilitated the launch of the H3Africa Communicable and Noncommunicable Diseases Working Groups.

NCDs of particular to the H3Africa initiative include:

  • Sickle cell disease and monogenic disorders
  • Stroke, CVD, and hypertension
  • Type 2 diabetes
  • Cancer

The report includes the following sections:

  • Section I – Executive Summary
  • Section II – Summary Recommendations of the H3Africa Working Groups
  • Section III – Harnessing Genomic Technologies Toward Improving Health in Africa, with sections on resources, infrastructure, education and training, population health and disease research, population health and disease research (NCDs included), pharmacogenomics, ethics, governance structure
  • Conclusions & Appendices

Members of the NCD Working Group include:

  • Bongani Mayosi, Chair – University of Cape Town
  • Albert G.B. Amoah, Vice-Chair – University of Ghana
  • Sonia Abdelhak – Institut Pasteur
  • Clement Adebamowo – Institute of Human Virology, Nigeria
  • Adebowale Adeyemo – National Institutes of Health (NIH)
  • Richard Cooper – Loyola University Chicago
  • Michael Hayden – University of British Columbia
  • Winston Hide – South African National Bioinformatics Institute
  • Bernard David Keavney – Newcastle University, British Heart Foundation
  • Patricia Marshall – Case Western Reserve University
  • Mark McCarthy – University of Oxford, Wellcome Trust
  • Olunfunmilayo Olopade – University of Chicago
  • Rajkumas Ramesar – University of Cape Town
  • Michele Ramsay – University of the Witwatersrand