Released by The Lancet Commission on Reframing NCDs and Injuries for the Poorest Billion (The Lancet NCDI Poverty Commission) in September 2020, this landmark report highlights key findings and recommendations demonstrating the magnitude and pattern of the NCDI burden in several low and low-middle income countries (LLMICs) in Sub-Saharan Africa, the Caribbean, and South Asia as well as emphasizing the disparities existing in care and resources available for NCDs and injuries.